Women's International Pharmacy E-Newsletter March 2012

Moods and Hormones: Emotional Health and Well-Being Throughout the Lifecycle

Publicaiton: A Lifetime of ProgesteroneJust mention those three little letters - PMS - and you're bound to get a reaction. Women nod in sympathy; men cringe at the thought. Everyone seems to know someone whose moods go through a "Jekyll and Hyde" type of transformation during that time of the month.

But the emphasis on PMS and its effects on a woman's moods seems blown out of proportion, especially in light of the fact that a woman's life is a continuum of hormonal upheavals that affect her moods. From puberty through menopause, women experience a continuous cycle of hormonal fluctuations that affect brain chemistry and, therefore, their moods.

This physiological fact of life may partially explain why "depression and anxiety disorders are 2-3 times more common in women than in men," a worldwide, cross-cultural phenomenon, according to Dr. Elizabeth Lee Vliet. this is a serious issue, which demands that we look beyond the all-too-common jokes about PMS to get a better understanding of how hormones affect a woman's emotional health and well-being, throughout her lifetime.

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Hormones, Moods & Emotion:
An Interview with Dr. Phyllis Bronson

Written by Carol Petersen, RPH, CNP - Women's International Pharmacy

We had an opportunity to speak with Dr. Phyllis Bronson, a recognized expert on the influence that hormones have on moods and emotions. Dr. Bronson holds a doctorate in molecular chemistry, and she currently teaches and continues to conduct research at the University of Denver. Her doctoral thesis focused on the molecular structure of progesterone; specifically, the significant molecular difference in the fat-soluble structure of "real" progesterone and the water-soluble structure of medroxyprogesterone, and how this difference impacts a person psychologically.

Dr. Bronson's work as a clinical biochemist enables her to continue to explore the relationships between hormones and psychology, gathering data as she works alongside practitioners while assisting them with patients. in fact, Dr. Bronson is currently working on a book with the tentative title Hormones, Mood and Emotion, Finding Balance As We Age, which intends to bring the observations she has amassed through her years of research to the general public.

One of the things we learned during our interview is Dr. Bronson's dislike for the word "anti-aging" when it comes to describing hormone therapies. She explained that she sees the body more....

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Online Health Library

We are proud to make available online, our popular "Connections" newsletters. These informational newsletters cover a wide range of hormone related health topics including:

  • Compounded Bioidentical Hormones
  • Breast Health Awareness
  • Male Hormones
  • Menopause
  • PMS
  • Progesterone
  • Skin
  • Thyroid Imbalances
  • Vitamin B12
  • Vitamin D
  • And more! 

We currently have over 25 topics available and are adding more on a regular basis. Check out the full list here.

If there is a particular topic you would like us to feature, please let us know by emailing us at info@womensinternational.com. As always we appreciate your feedback!



Staff at Women's International Pharmacy






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In This Issue
Moods and Hormones
Hormones, Moods & Emotion: An Interview with Phyllis Bronson
Online Health Library

Coming Events:

We will be at the following conferences:


Women's Health 2012 20th Annual Congress
March 16-18, 2012
Washington, DC


CANP 35th Annual Educational Conference
March 21-24, 2012

Please visit our website for our full conference schedule.




Mortar and Pestle

Thyroid, Progesterone and Mood

Provided by

Kathy Lynch, Pharm.D - Women's International Pharmacy

The simultaneous use of T3 with antidepressant therapy has been shown to improve mood. The use of progesterone has also been associated with positive mood changes. Is there a link between these two hormones?

There is, at least according to Michael Biamonte C.C.N. He maintains that progesterone helps zinc and potassium remain in the cell. Cellular zinc and potassium help T4 cross into the cell. Once in the cell, these minerals speed up the conversion of the inactive T4 to the active T3 hormone.

Progesterone also offsets the sometimes negative effect that estrogen has on thyroid hormones. Low progesterone levels allow estrogen to overpower thyroid function. In addition, progesterone controls high levels of copper (caused by too much estrogen) and calcium, both of which can interfere with thyroid function. .


"A pilot effectiveness study: placebo-controlled trial of adjunctive L-triiodothyronine (T3) used to accelerate and potentiate the antidepressant response."
Posternak M, et al. Int J Neuropsychoparmacol. 2008 Feb;11(1):15-25

"The relationship between progesterone and thyroid." Michael Biamonte, C.C.N

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